Archive for May, 2008

AGING: The Disease, The Cure, The Implications

May 19, 2008

Aging 2008 image

On Friday, June 27th, leading scientists and thinkers in stem cell research and regenerative medicine will gather in Los Angeles at UCLA for Aging 2008 to explain how their work can combat human aging, and the sociological implications of developing rejuvenation therapies.

Aging 2008 is free, with advance registration required at http://www.mfoundation.org/Aging2008/

There’s a press release here, and you can find more information on the official Aging 2008 website.

If you are not familiar with longevity science, Aubrey de Grey’s TED talk is a good starting point. If that intrigues you, his book Ending Aging is the next logical step.

Update Great news! I email Jeff Hall, the coordinator of Aging 2008, to ask if videos of the event would be made available online. He answered that they will “be filming the entire event and putting it up on youtube.”

‘Fold It’ Media Coverage Clearinghouse

May 13, 2008

I wouldn’t normally do this, but my Fold It: The Protein Folding Game post generated quite a bit of attention, and it is obvious that many people are curious about the protein-folding game. So I figured that a central repository of media coverage might be helpful - more information might push a few people over the edge and convince them to try the game. Here’s what I’ve found so far:

If you see Fold It mentioned in the mainstream media or on a popular website, let me know in the comments and I’ll add it to the list.

Fold It: The Protein Folding Game

May 11, 2008

Fold It Protein Folding Game image

Fold It is a game developed by the Rosetta@Home team (learn more about distributed computing) under the direction of Dr. David Baker at the University of Washington.

It features a new approach to protein prediction. Instead of using a more or less brute-force approach, with a CPU trying lots and lots of possibilities and calculating which ones give the best results, the game uses the human brain’s pattern recognition abilities (with help from a few automated tools) to try to find the lowest-energy folded state of a protein.

It has the potential to be on the cutting edge of a new generation of scientific games that are fun to play, teach you things, and can actually help researchers.

Words are inadequate to describe it, so please watch the two videos below to get an idea.

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Virtual Reality Could Explain the Fermi Paradox

May 9, 2008

Galaxies from deep space photo

A recent article in Technology Review by Nick Bostrom generated a lot of discussion about the Fermi paradox, which states:

The size and age of the universe suggest that many technologically advanced extraterrestrial civilizations ought to exist. However, this hypothesis seems inconsistent with the lack of observational evidence to support it.

I’ll add my 2 cents to this discussion by saying that there’s a possibility that any civilization that becomes advanced enough discovers that physical reality can’t hold a candle to virtual reality and makes the transition (alien transubstantiation, to coin a phrase). This could explain why they haven’t colonized the galaxy, or why we aren’t bathed in their radio communications.

Virtual worlds can be, in theory, both much more pleasant to inhabit, with unlimited freedom and none of the downsides of an existence based on crude physical processes, and also much more energy-efficient. Even without cold computing, it would take a lot less energy for an advanced civilization to do all that it wants to do within a simulation than by moving atoms around.

As I mentioned before, they could also think much faster, subjectively pushing back the heat death of the universe (while at the same time making communication with ’slow’ beings almost impossible).

I haven’t read all the serious papers on SETI and the Fermi paradox yet, but I’m pretty sure this is not an original theory. It’s just something that I haven’t seen mentioned yet and that I think deserves thinking about.

Update: Just to make things clearer, the kind of virtual reality I’m envisioning here is not one where you connect a biological body to a machine that sends it sensory information (like in the Matrix, for example). What I’m thinking of could probably be called ‘mind uploading’. There is no physical body, because one is not required. Everything would be inside the virtual world, kind of like how an artificial intelligence would not require a physical presence other than its computing substrate.

See also: Order in the Universe and Pattern Recognition

Ancient Wisdom is Actually Early Draft

May 8, 2008

Meditations by Marcus Aurelius book photo

For the past few days I’ve been reading (among other things, of course…) Meditations by Marcus Aurelius, a roman emperor who lived from 121 to 180. He is known as one of the most important stoic philosophers.

One thing that has been on my mind while reading this is the fact that many people are very impressed by anything labelled “ancient wisdom” and have a bias towards giving it more weight than more recent thought. Part of that inclination is rational: If something has endured that long, there’s a good chance that it is because of its quality. But another part of it is not rational. It is based on the false parallel between the fact that older humans are generally considered wiser and the fact that the text is old.

From our point of view, the text is old. But from the point of view of human knowledge, old texts are ‘younger’ than modern texts.

So while I appreciate many of Marcus Aurelius’ stoic principles (look for truth, mind your own business, don’t waste your time on frivolous things, clearly define what matters to you so you can better stick to it, be open to have your mind changed by evidence, eliminate the unnecessary, etc), I simply chuckle when I read about his conception of the universe, the gods, reality, destiny, dualism (soul separate from body), death, etc. This is the best information that was available at the time, but compared to what we know now, it’s clearly archaic and if the roman emperor had been born today, he probably wouldn’t believe what he believed then (not to mention his positions on slaves, women, homosexuals, etc).

Yet some people will automatically give more weight to these ideas than to ideas that come from more contemporary sources because they come from “ancient wisdom”. If you suffer from that bias, you should recognize it, look back on how it might have influenced you in the past, and keep it in mind for the future. Judge ideas on their own merit, not on their capacity to endure the passage of time. With some things, it doesn’t matter too much (f.ex. morality). With others, it changes everything (scientific fields such as cosmology, biology, physics, etc).

If more people realized this, fewer Bronze Age myths would be taken seriously.